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www PharmacvPrep.Com Anti-Helments Drugs

Clinical Use: Pinworm and wh ipworm infections
Contraindicated in pregnancy

Pyrantel pamoate:
Mechanism: Depolarizing neuromuscular blocker, which causes paralysis of nematodes.
Clinical use: Hookworm infections, pinworm infections, Roundworm.
Caution.:.Red color urine, feces, stains on vomiting.

Praziquantel:
Mechanism: Increase membrane pemteability to Ca2+ using muscular contraction and paralysis oflhe
nematode muscles.
Clinical Use: Drug of choice for Schistosomiasis, clonorchiasis, and pranomiasis.

Niclosamide:
Clinical Use: Infections from ingestion of beef, pork, and fish.

Anti-Helminth Drugs Tips

Pinworm infections cnn treated by:
Non-medical recommendation in patients with pinwonn infection include: Bathing every
morning, regular cleaning of undergannents, bedding etc. Handwash, during the fol lowing week
of treatment all family members should wear cotton underpants. Frequent wash ing oftoileLseats.
Which antihelmenthic drug can cause red color body fl uids, such as urine, saliva etc? Pyrantel
pamoate

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